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Every batch is independently tested by an ISO/IEC 17025:2017 accredited laboratory.
Includes COA with every order.

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IGF-1 LR3

980 in stock

Original price was: $179.00.Current price is: $119.00.

980 in stock

3RD Party Tested

COA Verified

High Purity

99% + Purity

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Key Benefits (Research Use Only)

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Key Benefits

Research Use Only

Certified purity. Consistent performance. Every batch

High-affinity peptides designed for targeted discover

Consistently top-rated for purity and batch-to-batch stability

High purity lyophilized powder

For laboratory research purpose only

Category Peptides

Quality you Can Trust

Every batch is independently tested by an ISO/IEC 17025:2017 accredited laboratory.
Includes COA with every order.

These products are intended for laboratory research purposes only, and are not for human or animal consumption. The products are not intended to diagnose, treat, cure, or prevent any disease. The products should not be used as a food, drug, cosmetic, or other household use.

Description

IGF-1 LR3 is a long-acting analog of insulin-like growth factor-1 (IGF-1) engineered by substituting an arginine at position 3 and extending the peptide chain to enhance biological stability in research systems.

In laboratory studies, IGF-1 LR3 is investigated for its role in:

IGF-1 receptor (IGF-1R) activation pathways
Cellular growth and differentiation signaling models
Protein synthesis pathway research
Glucose metabolism and insulin signaling interactions
Cell survival and proliferation pathway studies (preclinical)
Muscle and tissue cell culture research models

Key Scientific Features

Long-acting IGF-1 analog (LR3 modification)
Reduced binding affinity to IGF-binding proteins (research context)
Enhanced receptor activity duration in experimental systems
High-purity synthetic peptide (HPLC/MS verified)
Lyophilized formulation for stability
Full Certificate of Analysis (COA) included
Manufactured under controlled ISO-aligned laboratory conditions

Research Applications (Non-Therapeutic)

Based on peer-reviewed scientific literature not intended as medical claims.

IGF-1 LR3 is commonly used in research involving:

IGF-1 receptor signaling pathway studies
Cellular proliferation and differentiation models
Protein synthesis and anabolic signaling research (cellular models)
Glucose metabolism and insulin pathway interaction studies
Tissue culture and regenerative biology research models
Cell survival and anti-apoptotic signaling investigations

Scientific Evidence & References

NIH PubChem – IGF-1 Protein Overview
IGF-1 Signaling Pathways Review (NCBI)
Growth Factor Biology and IGF System Review

These references describe IGF-1 and its analogs as key regulators of cellular growth signaling, metabolism, and receptor-mediated biological activity in experimental systems.

Mechanism of Action

In laboratory models, IGF-1 LR3 functions by:

Binding to the IGF-1 receptor (IGF-1R)
Activating intracellular signaling pathways (e.g., PI3K/Akt and MAPK cascades)
Modulating protein synthesis and cellular growth signaling
Supporting studies of metabolic and proliferative cellular responses

Handling & Stability

Store at 2–8°C (refrigerated)
Protect from light and heat exposure
Avoid repeated freeze-thaw cycles
Use sterile laboratory handling procedures
Reconstitute only in appropriate research-grade solvents

Why Researchers Choose IGF-1 LR3

Long-acting IGF-1 analog for extended signaling studies
Strong relevance in cellular growth pathway research
High analytical purity and batch consistency
Widely referenced in cell biology and metabolic research
Reliable performance in controlled experimental systems

Important Notice

For Research Use Only. Not for human or veterinary use.
This product is not a drug, supplement, cosmetic, or therapeutic agent. It is intended strictly for laboratory research and analytical applications.

FAQ's

Research Use Only / Not for Human Consumption

These products are intended for laboratory research purposes only, and are not for human or animal consumption. The products are not intended to diagnose, treat, cure, or prevent any disease. The products should not be used as a food, drug, cosmetic, or other household use. By accessing this website or purchasing from this website, you agree that that it is your sole responsibility to ensure compliance with applicable laws and regulations within your jurisdiction; and you understand and acknowledge that no information on this website should be construed as medical advice.

Product Testing

We verify every batch of every product through accredited, independent third-party laboratories. Since each product requires unique analytical methods and equipment, we collaborate with specialized laboratories and PhDs in analytical and organic chemistry to design our testing protocols.

Analytical techniques we utilize include: NMR, FTIR, HPLC, LC-MS, GC-MS, TLC, ICP-MS, Gravimetry, UV-Vis, Titration, Melting Point, and Organoleptics.
We primarily test for purity, content, sterility, and endotoxins (LPS).

Product Appearance Variations

Variations in color, texture, odor or even biochemical properties may occur due to polymorphy (differences in crystal structure).These variations do not compromise product quality.

Peptide Form

Our peptides are provided in lyophilized powder form to ensure maximum stability. In any other format, peptide integrity would rapidly degrade before reaching the customer.

Optimal storage: Below –20 °C.
Short-term storage: Refrigeration at 4 °C for up to 2 years.
Room temperature tolerance: 4–6 weeks with minimal degradation if protected from direct sunlight (suitable for international shipping).

Peptide Top Colors

Images on our site display white tops for illustration purposes only. In practice, vial tops may vary in color to help our staff distinguish products during processing.

Peptide Powder Appearance

Lyophilized peptides typically form a solid cake. However, during transit, the cake may break or appear uneven. This is an aesthetic issue only and does not impact quality, potency, or purity.

Some peptides and proteins may appear larger due to buffering requirements. This is normal.

Storage Instructions

Storage instructions are provided on each product listing and product label.

General storage: Store in a cool, dry place away from heat, moisture, and sunlight.
Best practice: Refrigeration or freezing is recommended for long-term stability.

Solution Flakes, Precipitation, and Separation

Solution-based products may occasionally:

Crystallize (form flakes)
Precipitate (fall out of suspension)
Separate (form layers)
Lose homogeneity

This typically occurs during cold transit or accidental freezing. To restore uniformity:

Warm the vial in 50–70 °C water for 5–10 minutes.
Shake vigorously to re-suspend.

If the product does not return to homogeneity, please contact us.

Extreme Temperature Exposure

All molecules degrade over time, but proper storage significantly slows this process.

Low temperature exposure: Generally safe; may cause precipitation in solutions but does not accelerate degradation.
High temperature exposure: Prolonged exposure may accelerate degradation.
- Example: A product requiring room temperature storage exposed to 115 °F for a few days will not show measurable degradation once properly stored again.
Cold-storage products (–20 °C): Short-term exposure (<24h) to ambient temperatures does not significantly degrade the product unless oxygen, moisture, or sunlight are also present.

Accidental Exposure or Ingestion

Contact your local toxicologist. United States: Poison Help Line — 1-800-222-1222
Seek immediate medical attention.
Always handle products using proper PPE.
Refer to the product’s SDS for safety guidelines.