PT-141 (Bremelanotide) — Synthetic Peptide for Neuroendocrine & Sexual Function Research
PT-141, also known as Bremelanotide, is a laboratory-synthesized peptide derived from melanocortin receptor agonists. It is widely used in preclinical research to study sexual behavior, hormonal signaling, and central nervous system (CNS) pathways.
Mechanism of Action
PT-141 acts primarily through melanocortin receptors (MC3R and MC4R) in the brain, influencing neuroendocrine signaling and behavioral responses:
Neuroendocrine Modulation: Targets CNS melanocortin receptors to regulate hormone-related pathways
Sexual Function Effects: Modulates arousal and libido in preclinical models
CNS & Behavioral Research: Enables studies on peptide-mediated effects on neural circuits and signaling
Key Research Applications
Sexual Behavior Studies – Examining arousal, libido, and receptor-specific effects
Neuroendocrine Signaling Research – Investigating hormonal regulation and CNS pathways
Melanocortin Receptor Pharmacology – Studying MC3R/MC4R binding, receptor activation, and downstream signaling
Behavioral & Neurological Models – Evaluating peptide effects on mood, motivation, and CNS responses
Preclinical Therapeutic Research – Exploring receptor-targeted interventions and mechanistic studies
Peptide Specifications
Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Molecular Weight: ~1025 g/mol
Form & Size: 10 mg vials, lyophilized powder
Purity: ≥98% (HPLC/MS verified)
Storage: −20 °C, desiccated, protect from light
For Laboratory Research Use Only — Not for human or veterinary consumption. Intended solely for controlled experimental studies by qualified professionals.
